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| 趋化因子受体CX3CR1基因多态性与缺血性脑血管病的关系 | |
| 引用本文： | 于薇,张蕴莉,林闽,方伯言. 趋化因子受体CX3CR1基因多态性与缺血性脑血管病的关系[J]. 中国现代医生, 2008, 46(4): 27-28 |
| 作者姓名： | 于薇 张蕴莉 林闽 方伯言 |
| 作者单位： | 1. 辽宁医学院,辽宁锦州,121001 2. 辽宁医学院附属第一医院检验科,辽宁锦州,121000 3. 吉林大学口腔医学院牙体牙髓病科,长春,130000 4. 辽宁医学院附属第一医院神经内科,辽宁锦州,121000 |
| 摘 要： | 缺血性脑血管病最重要的病理生理基础是颅内血管的动脉粥样硬化。CX3CRl两个单核苷酸多态性T280M、V249I在动脉粥样硬化中已有报道，这个位点的遗传变异可能影响缺血性脑血管病的遗传易感性。 |
| 关 键 词： | 缺血性脑血管病 动脉粥样硬化 基因多态性 CX3CRI |
| 文章编号： | 1673-9701(2008)04-27-03 |
| 修稿时间： | 2007-09-21 |
The Relationship between the Polymorphisms of Fractalkine Receptor CX3CR1 and Ischemic Cerebrovascular Disease |
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| YU Wei,ZHANG Yunli,LIN Min,FANG Boyan. The Relationship between the Polymorphisms of Fractalkine Receptor CX3CR1 and Ischemic Cerebrovascular Disease[J]. , 2008, 46(4): 27-28 | |
| Authors: | YU Wei ZHANG Yunli LIN Min FANG Boyan |
| Affiliation: | YU Wei^1 ZHANG Yunli^2 LIN Min^33 FANG Boyan^4 1.Liaoning Medical College,Liaoning 121001;2.Department of Laboratory, the First Affiliated Hospital of Liaoning Medical College, Liaoning 121000;3.Department of Endodontic Diease, School of Stomatology, Jilin University, Changchun 130000;4.Department of Neurology, The First Affiliated Hospital of Liaoning Medical College, Jinzhou 121000 |
| Abstract: | The atherosclerosis of intracranial vessels is thought to be the major pathological mechanism of ischemic stroke The contribution to atherosclerosis of two CX3CR1 single nucleotide polymorphisms, V249I and T280M has been recently reported. Genetic variation at this locus may affect susceptibility to ischemic stroke. |
| Keywords: | Ischemic cerebrovascular disease Athemsclerosis Polymorphism CX3CR1 |
| 本文献已被 维普 万方数据 等数据库收录！ | |