| 68例急性药物性肝炎分析 |
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| 引用本文： | 王庆治,王素娟,杜鹏程,张丽萍,张帮杰.68例急性药物性肝炎分析[J].中国民康医学,2012,24(13):1538-1540. |
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| 作者姓名： | 王庆治 王素娟 杜鹏程 张丽萍 张帮杰 |
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| 作者单位： | 新乡医学院第三附属医院消化科,河南,新乡,453000 |
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| 摘 要： | 目的:分析诱发急性药物性肝病的药物种类、临床特点及提高对药物性肝病的认识。方法:回顾性分析68例急性药物性肝炎,对其病因及临床特点进行分析。结果:导致急性药物性肝炎药物以抗结核药物最常见,占29.4%(20/68);其次,中药占25.0%(17/68);然后,抗生素类药物占14.7%(10/68)。临床类型中肝细胞损伤型占30.9%(21/68)、胆汁淤滞型占52.9%(36/68)、混合型占16.2%(11/68)。结论:急性药物性肝炎可由多种药物引起,早期及时停用损肝药物是治疗的关键。
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| 关 键 词： | 药物 肝病 急性药物性肝炎 |
Clinical analysis of 68 cases of acute drug induced liver diseases |
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| WANG Qing-zhi
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WANG Su-juan
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DU Peng-cheng
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ZHANG Li-ping
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ZHANG Bang-jie.Clinical analysis of 68 cases of acute drug induced liver diseases[J].medical journal of chinese peoples health,2012,24(13):1538-1540. |
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| Authors: | WANG Qing-zhi WANG Su-juan DU Peng-cheng ZHANG Li-ping ZHANG Bang-jie |
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| Institution: | ,et al(Department of Gastroenterology,the third affiliated hospital of Xinxiang medical college,Xinxiang 453000,China) |
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| Abstract: | Objective:To the etiology,clinical characteristics and improve the understanding of acute drug-induced liver disease.Methods:We investigated the causes,incidence and clinical characteristics of drug-induced liver disease in 68 cases retrospectively.Results: The most common agent to induce liver disease was ant tubercular drug 29.4 %(20/68),the second was traditional Chinese medicine 25.0%(17/68),the third was antibiotics 14.7%(10/68).There were 21(30.9%),cases of liver cell injury,36(52.9%) cases of cholestasis and 11(16.2%) mixed cases.Conclusions: Almost all agents used in clinic may cause liver disease.The principal management for the disease is discontinuation of the suspected drugs. |
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| Keywords: | Drug Liver disease Acute drug-induced liver disease |
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