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两种剂量丙种球蛋白治疗新生儿溶血病的疗效分析
引用本文:周福根,龙文香,陈建辉.两种剂量丙种球蛋白治疗新生儿溶血病的疗效分析[J].中国民康医学,2012,24(15):1839-1840.
作者姓名:周福根  龙文香  陈建辉
作者单位:吉安市妇幼保健院儿科,江西,吉安,343000
摘    要:目的:观察两种剂量丙种球蛋白(IVIG)治疗新生儿ABO溶血病(ABO HDN)的临床疗效。方法:将ABO HDN患儿随机分成两组,对照组给予IVIG 0.5 g/(kg·d),连用3天,治疗组给予IVIG 1 g/(kg·d),连用2天。观察两组黄疸消退时间,治疗后24小时、72小时血胆红素值。结果:两组相比较,治疗组黄疸消退时间短,治疗后24小时、72小时血胆红素值低,有统计学意义。结论:治疗ABO HDN应用大剂量IVIG1 g/(kg·d),连用2天]取得较好的疗效。

关 键 词:新生儿  ABO溶血病  丙种球蛋白

The Therapeutic Effects of Two Doses of Gammaglobulin for neonatal hemolytic disease
ZHOU Fu-gen , LONG Wen-xiang , CHEN Jian-hui.The Therapeutic Effects of Two Doses of Gammaglobulin for neonatal hemolytic disease[J].medical journal of chinese peoples health,2012,24(15):1839-1840.
Authors:ZHOU Fu-gen  LONG Wen-xiang  CHEN Jian-hui
Institution:(Ji’an maternal and child healthy hospital,Jiangxi 343000,China)
Abstract:Objective:To observe the therapeutic effects of two doses of gammaglobulin(IVIG) for ABO hemolytic disease of newborn(ABO HDN).Methods:The Children with ABO HDN were randomly divided into two groups,control group was given IVIG 0.5g /(kg·d),once every three days,the treatment group were given IVIG 1g /(kg·d),once every two days.Observed regression of jaundice,monitoring of serum bilirubin.Results: Compared with two groups,the treatment group was short time jaundice,24 hours,72 hours after treatment,that was low serum bilirubin,it was statistically significant.Conclusions: Treatment of high dose IVIG 1g /(kg·d),once every 2 days] for ABO HDN achieved better results.
Keywords:Newborn  ABO hemolytic disease  Gammaglobulin
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