| 阿立哌唑合并氯氮平治疗难治性精神分裂症的临床研究 |
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| 引用本文： | 周之平,汪富军,沈平.阿立哌唑合并氯氮平治疗难治性精神分裂症的临床研究[J].中国民康医学,2012,24(17):2064-2066. |
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| 作者姓名： | 周之平 汪富军 沈平 |
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| 作者单位： | 南京市青龙山精神病院,江苏,南京,211123 |
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| 摘 要： | 目的:了解阿立哌唑与氯氮平合并治疗难治性精神分裂症的治疗效果与不良反应.方法:对45例服用氯氮平的难治性精神分裂症患者联合使用阿立哌唑,在治疗前、治疗后2、4、8、12周末采用PANSS量表评定疗效,TESS量表评定不良反应.结果:联合使用阿立哌唑后PANSS量表分显著下降(P<0.05),总不良反应显著减少(P<0.05).结论:阿立哌唑合并氯氮平治疗难治性精神分裂症疗效好,安全性高,可以作为一个较好的选择.
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| 关 键 词： | 难治性精神分裂症 阿立哌唑 氯氮平 |
The clinical research of Aripiprazole combined with Clozapine in refractory schizophrenia |
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| ZHOU Zhi-ping
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WANG Fu-jun
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SHEN Ping.The clinical research of Aripiprazole combined with Clozapine in refractory schizophrenia[J].medical journal of chinese peoples health,2012,24(17):2064-2066. |
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| Authors: | ZHOU Zhi-ping WANG Fu-jun SHEN Ping |
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| Institution: | (Nanjing Qinglongshan mental hospital,Jiangsu 211123,China) |
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| Abstract: | Objective:To study the aripiprazole combined with clozapine for the for the treatment in refractory schizophrenia therapeutic efficacy and side effect respectively.Methods:45 patients of clozapine in refractory schizophrenia combined with aripiprazole,PANSS and TESS were used to assess the therapeutic efficacy and side effect respectively before treatment、after treatment with 2、 4、 8、12 weekend.Results: The patients combined with aripiprazole PANSS scores decreased significantly(P<0.05),the total side effect respectively decreased significantly(P<0.05).Conclusions: Aripiprazole combined with clozapine in the treatment of refractory schizophrenia has good therapeutic efficacy,high safety,can be used as a good choice. |
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| Keywords: | Refractory schizophrenia Aripiprazole Clozapine |
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