31例托拉塞米注射剂治疗急性左心衰竭的临床分析

目的:探讨托拉塞米对急性左心衰竭的疗效和安全性。方法:将62例急性左心衰竭患者随机分为托拉塞米组(31例)和呋塞米组(31例),托拉塞米组应用托拉塞米20～80 mg/d,呋塞米组应用呋塞米20～100 mg/d,余治疗相同。观察两组的疗效、肾功能、电解质、尿酸、血糖、甘油三脂(TG)和不良反应。结果:①托拉塞米组心力衰竭缓解率为93.55%;呋塞米组心力衰竭缓解率为54.84%,组间差异有统计学意义(P<0.05);②两组间比较总不良反应发生率(P>0.05)差异无统计学意义,但两组低钾比较(P<0.05)差异有统计学意义。结论:托拉塞米治疗急性左心衰竭疗效显著,安全性好。

Clinical analysis of 31 cases of Torasemide injection in the treatment of acute left ventricular failure

Objective:To explore the efficacy and safety of Torasemide in the treatment of acute left heart failure.Methods:62 patients with acute left heart failure were randomly divided into Torasemide group(31 cases) and Furosemide group(31 cases).Torasemide 20-80mg/d was applied to Torasemide group and Furosemide group received Furosemide 20-100mg/d.Then we observed the curative effect,kidney function,electrolyte,uric acid,blood glucose triglycerides(TG) and adverse reaction of the two groups.Results: ① Torasemide group’s remission rate of heart failure was 93.55%;while the Furosemide group’s remission rate of heart failure was 54.84%.The difference between groups was statistically significant(P<0.05).② Comparison of difference in the total adverse reaction rate(P>0.05) between the two groups had no statistical significance,but the comparison(P < 0.05) of difference in low potassium was statistically significant.Conclusions: Torasemide is more effective and safe in the treatment of acute left heart failure.