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| 弱视患者的皮层视觉运动觉 | |
| 引用本文： | 梁平,张志强,卢光明,邵庆.弱视患者的皮层视觉运动觉[J].眼视光学杂志,2005,7(3):152-154. |
| 作者姓名： | 梁平 张志强 卢光明 邵庆 |
| 作者单位： | 1. 深圳职业技术学院,眼视光技术专业,广东,深圳,518055 2. 南京军区总医院,江苏,南京,210016 3. 南京医科大学第一附属医院,江苏,南京,210029 |
| 基金项目： | 江苏省教育厅自然科学基金项目（02KJB320005） |
| 摘 要： | 目的采用功能磁共振成像技术对弱视的视觉运动功能进行研究。方法采用组块设计方式，对9例弱视患者与8例健康志愿者分别进行两侧单眼的旋转光栅刺激、1．5T磁共振扫描和sPM软件离线处理。分别比较弱视组及对照组两单眼间不同的反应水平。结果弱视患者弱视眼的反应体素数目及反应强度均较正常眼低（tAN=3．47，P〈0．05；tAT=2．57，P〈0．05）；正常人双眼间差异无显著性（tAN=1．28，P〉0．1；tNT=-0．02，P〉0．5）。结论弱视患者视皮层视觉运动觉功能下降。 |
| 关 键 词： | 弱视 视觉运动觉 皮层 功能磁共振成像／方法 |
| 文章编号： | 1008-1801(2005)03-0152-03 |
| 收稿时间： | 2005-01-19 |
| 修稿时间： | 2005-07-08 |
Study about visual motion of amblyoia in cortex |
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| Liang Ping;Zhang ZhiJiang;Lu GuangMing;Shao Qing.Study about visual motion of amblyoia in cortex[J].Chinese Journal of Optometry & Ophthalmology,2005,7(3):152-154. | |
| Authors: | Liang Ping;Zhang ZhiJiang;Lu GuangMing;Shao Qing |
| Abstract: | Objective To investigate the amblyopia pathology about the visual motion using functional MRI technique.Methods Nine amblyopia patients and 8 healthy volunteers were included in for the tests with epoch fMRI paradigm, stimulated by rotating grating with each monocular. Data acquisition was performed in 1.5 Tesla MRI scanner, processed by SPM software offline, comparisons were made between the number of activated voxel of eyes.Results The activation level (voxel number and T value of activation) of amblyopia eyes was lower than good eyes in amblyopia patients (t_(AN)=3.47, P<0.05; t_(AT)=2.57, P<0.05). There was no statistical interocular difference in control cases (t_(NN)=1.28, P>0.1; t_(NT)=-0.02, P>0.5).Conclusion The activation of visual motion of amblyopia eyes decreases. It may suggest that there is functional deficits in visual motion area of cortex. |
| Keywords: | amblyopia visual motion cortex functional MRI/methods |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |