Spongiadioxins A and B, two new polybrominated dibenzo-p-dioxins from an Australian marine sponge Dysidea dendyi. |
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| Authors: | N K Utkina V A Denisenko O V Scholokova M V Virovaya A V Gerasimenko D Y Popov V B Krasokhin A M Popov |
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| Affiliation: | Pacific Institute of Bioorganic Chemistry, Russian Academy of Sciences, 690022 Vladivostok, Russia. utkinan@mail.ru |
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| Abstract: | Two new cytotoxic tetrabromodibenzo-p-dioxins, spongiadioxins A (1) and B (2), were isolated from an Australian marine sponge Dysidea dendyi. The structures of these compounds were established by 1D and 2D NMR spectroscopy, X-ray analysis of the methyl ether of spongiadioxin A (3), and synthesis of the methyl ether of spongiadioxin B (4) from diphenyl ether (9) isolated from Dysidea herbacea. |
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