Abstract: | Tuberculosis morbidity in the adults, who were close relatives of infected children, is 5.2 times higher than the mean rate for the adult population; of them the individuals having 21 mm or more and 13-18 mm papules to the Mantoux test with 2 TU PPD-L showed 10.6 and 3.8-fold rates, respectively. 40% of the infected were subjects aged 18 to 29 years and living in the families with affected parents. The group under observation included persons highly allergic to tuberculin in 6.3 times more than amongst all the examined adults. The differential examination and observation of subjects at a risk of endogenous reactivation and belonging to the families of the infected groups are shown to be important in optimizing tuberculosis detection and prevention. |