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养胃安神口服液治疗中老年人失眠的实验研究
引用本文:白亚平,吕金仓,刘二军,王声强,刘雅芹,李振彬.养胃安神口服液治疗中老年人失眠的实验研究[J].河北中医,2004,26(8):639-640.
作者姓名:白亚平  吕金仓  刘二军  王声强  刘雅芹  李振彬
作者单位:河北医科大学第一医院中医科,石家庄,050031;中国人民解放军白求恩国际和平医院中医科,石家庄,050082
基金项目:河北省 2 0 0 4年科技研究与发展指导计划项目 (编号 :0 42 76169)
摘    要:目的:研究养胃安神口服液对小鼠的镇静、安神和促进消化作用,揭示该药对中老年人失眠的作用机制。方法:通过抖笼换能器法观察该药对小鼠的镇静作用;与其他安眠药物对照,观察该药对戊巴比妥钠阈剂量小鼠睡眠时间的影响;通过灌胃给药,观察该药对小鼠小肠墨水推进率的影响。结果:大剂量养胃安神口服液能抑制小鼠自发活动,对小鼠睡眠与戊巴比妥钠有协同作用,能促进小鼠小肠蠕动。结论:养胃安神口服液具有明显的镇静、安神和促进消化作用。

关 键 词:养胃安神口服液  失眠  消化  实验研究
文章编号:1002-2619(2004)08-639-02

Experimental study of insomnia treatment of middle - aged and elderly people by Yangwei Anshen oral liquid
BAI Yaping,LU Jincang,LIU Erjun,et al..Experimental study of insomnia treatment of middle - aged and elderly people by Yangwei Anshen oral liquid[J].Hebei Journal of Traditional Chinese Medicine,2004,26(8):639-640.
Authors:BAI Yaping  LU Jincang  LIU Erjun  
Institution:BAI Yaping,LU Jincang,LIU Erjun,et al. Traditional Chinese Medicine,The First Hospital of Hebei Medical University,Shijiazhuang 050031
Abstract:Objective To study the effect of Yangwei Anshen oral liquid on sedation, sleep and digestion of experimental rats, and discover the mechanism of oral liquid on elder patients of insomnia. Methods The oral liquid and other medicine wree observed in sedation and the sleep time of mice when they were given in a subliminal dose of Nembuta. The mice were feed with oral liquid and other medicines to observe effect of the oral liquid on mouse's intestine movement. Results Yangwei Anshen oral liquid could inhibit the spontaneous activity and cooperate with pentobarbital sodium to affect the sleep time of mice. It can accelerate small intestine movement. Conclusion The Yangwei Anshen oral liquid has obvious effect on sedation, hypnosis and helping digestion.
Keywords:Yangwei Anshen oral liquid  Insomnia  Digestion  Experimental study
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