Formation and antiviral effect of N-(adamantyl-91))-thiocarbamides

Formation and Virus Inhibitory Activity of N-[1-Adamantyl]-thioureas Interaction of 1 -amino-adamantane ( 1 ) with isothiocyanates ( 2 ) results in the formation of N-[ 1 -adamantyl]-thioureas ( 3 ). Chemical structure proof of 3 has been adduced by an independent synthesis involving the reaction of 1 -adamantyl-isothiocyanate ( 4 ) with the corresponding amines ( 5 ).