膀胱肿瘤265例临床分析

目的：总结膀胱肿瘤发病规律，探讨膀胱肿瘤分期、分级以及治疗方法与预后的关系，进一步指导膀胱肿瘤的诊断与治疗。方法：对我院１９８３～１９９５年间收治的膀胱肿瘤２６５例进行临床分析，统计不同分期肿瘤与不同手术方式术后３年及５年生存率，同时对控制术后肿瘤复发的不同方法进行比较。结果：２６５例患者中，有病理结果者２３９例，其中尿路上皮性肿瘤２１０例（８７．８７％）、非上皮性肿瘤２９例（１２．１３％），治疗以手术治疗为主，采用术式取决于肿瘤的大小及浸润程度。术后随访Ｔ１、Ｔ２、Ｔ３、Ｔ４期肿瘤３年存活率分别为９２．８６％、６８．５２％、２７．７８％、０；５年存活率分别为８２．５２％、５４．１７％、２１．４３％、０。结论：膀胱肿瘤的分期和分级是判断预后的决定性因素，即肿瘤细胞分化程度与浸润和预后呈正相关；术后膀胱药物灌注是预防复发的最佳方案。

The Clinical Study of 265 Cases of Bladder Tumor

Objective: For the guidance of further diagnosis and treatment of bladder tumor, the pathogenic regularity of bladder tumor was summarized and the relation between the stage, grade,the method of treatment and prognosis was inquired.Methods: 265 cases of bladder tumor that we had treated during 1983～1995 were studied, The survival rates postoperatively at 3 and 5 years in differents stage bladder tumor were summarized. Meanwhile,the different methods for the prevention of tumor recurrence postoperatively were compared Results: 239 cases were examinated histologically.Of the 239 cases;210 cases were epithelial tumor (87.87%).29 cases were non epithelial tumor(12.13%).The survival rate at 3 years in T1,T2,T3 and T4 stage bladder tumor were 92.86%,68.52%,27.78% and 0 seperately, and that at 5 years were 82.52%,54.17%,21.43% and 0 sepeartely.Conclusion: The stage and grade of bladder tumor is a primary factor to judge prognosis. There is positive correlation between the differentiation, infiltration of tumor and pronosis.The intravesical drugs after operation is the best method to prevent recurrence.