Malignant oral tumors in iran: ten-year analysis on patient and tumor characteristics of 1042 patients in Tehran |
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Authors: | Sargeran Katayoun Murtomaa Heikki Safavi Seyed Mohammad Reza Vehkalahti Miira Teronen Olli |
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Institution: | Oral Public Health Department, Institute of Dentistry, University of Helsinki, PO Box 41, Helsinki, FI-00014, Finland. katayoun.sargeran@helsinki.fi |
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Abstract: | This study analyzed characteristics of oral cancer patients from Tehran, Iran, and their tumors. Data came from the patient records of 30 major hospitals in Tehran. Patients (n = 1042), diagnosed with invasive oral cancer in 1993-2003, were classified by primary tumor site according to ICD-10 (C00-C10). Data were analyzed separately for lip, oral cavity and salivary gland tumors. Statistical evaluation included chi and t-test. Of all cases, 59% were male. Age for all cases ranged from 6-103 years, mean age was 58.8 years (SD 16; median 62); 89% were older than 40. Tumor site breakdown was 65% oral cavity, 21% major salivary glands and 14% lip. A clear gender difference (P < 0.001) appeared regarding the primary tumor sites: women dominated in oral cavity cancers and men in lip cancers. The most common cancer site was the tongue (32%), accounting for 50% of the oral cavity cancers. Histologically, 88% of all oral cavity and lip cancers were squamous cell carcinomas, 10% of those were in age =40, 42% in ages 41-64 and 48% >/= age 65. At the time of diagnosis, 59% of oral cavity cancers and 29% of lip cancers were at stage III or IV (P < 0.001). The results emphasize an urgent need for a national program focusing on early detection of oral cancers, including educational information addressed to oral health professionals. |
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