| 参芪扶正注射液配合化疗治疗大肠癌的临床观察 |
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| 引用本文： | 敬新蓉,陈健,闵敏,钟国成,岳伦莉,廖浩,王跃蓉. 参芪扶正注射液配合化疗治疗大肠癌的临床观察[J]. 现代肿瘤医学, 2007, 15(3): 384-386 |
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| 作者姓名： | 敬新蓉 陈健 闵敏 钟国成 岳伦莉 廖浩 王跃蓉 |
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| 作者单位： | 1. 四川大学华西医院人类疾病生物治疗教育部重点实验室肿瘤中心,四川成都,610041;解放军452医院肿瘤科,四川,成都,610061
2. 解放军452医院肿瘤科,四川,成都,610061 |
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| 摘 要： | 目的观察奥沙利铂(oxaliplatin)、亚叶酸钙(CF)、氟尿嘧啶(5-Fu)组成的FOLFOX4方案并用参芪扶正注射液及单用化疗治疗大肠癌的疗效及不良反应。方法67例接受化疗的大肠癌患者采用单盲法分为单用化疗组(对照组)及化疗并用参芪扶正注射液组(研究组)。结果研究组有效率(CR PR)57.14%,对照组有效率53.13%,差异无统计学意义(P>0.05);骨髓抑制、恶心、呕吐等反应较单纯化疗组轻,P<0.05;化疗后研究组CD3、CD4、CD4/CD8、NK细胞明显高于对照组,差异具有统计学意义(P<0.05)。结论参芪扶正注射液联用FOLFOX4方案与单用FOLFOX4方案化疗相比能减轻化疗毒副作用。
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| 关 键 词： | 参芪扶正注射液 配合化疗 大肠癌 |
| 文章编号： | 23968244 |
| 修稿时间： | 2006-02-24 |
Clinical efficacy of shenqi fuzheng injection combined with chemotherapy off advanced colorectal carcinoma |
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| JING Xin-rong,CHEN Jian,MIN Min,ZHONG Guo-cheng,YUE Lun-li,LIAO Hao,WANG Yue-rong. Clinical efficacy of shenqi fuzheng injection combined with chemotherapy off advanced colorectal carcinoma[J]. Journal of Modern Oncology, 2007, 15(3): 384-386 |
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| Authors: | JING Xin-rong CHEN Jian MIN Min ZHONG Guo-cheng YUE Lun-li LIAO Hao WANG Yue-rong |
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| Affiliation: | 1. Key Laboratoty of Biotherapy of Human Diseases of Ministry of Education, Cancer Center, West China Hospital, Sichuan University, Ghengdu 610041 ,China;2 Department of Oncology , Hospital 452 of PIA , Chengdu 610061, China. |
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| Abstract: | Objective: To observe the clinical effect of Shenqi Fuzheng injection combined with chemotherapy in treatment of advanced colorectal carcinoma. Methods: Total of 67 patients were randomly divided into chemotherapy combined Shenqi Fuzheng injection therapy group(trial group,TG)and simple chemotherapy group(control group,CG). Results: The efficacy rates in TG and CG were 57.14% and 53.13% respectively, there was no significant difference between the 2 group(P>0.05); Improvement in life quality and immune function was greater in TG than in CG(P<0.05). Conclusion: Shenqi Fuzheng injection combined with chemotherapy can enhance immune function and improve the life quality in patients with advanced colorectal carcinoma. |
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| Keywords: | Shenqi Fuzheng injection chemotherapy advanced colorectal carcinoma |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
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