18F-FDG PET/CT在原发灶不明的脑转移瘤中的诊断价值

目的 探讨18F-FDG PET/CT在查找原发灶不明的脑转移瘤中的价值。 方法 回顾性分析17例原发灶不明的脑转移瘤患者的全身18F-FDG PET/CT检查资料。 结果 17例患者均经活检确诊原发灶，准确率100%。原发性肺癌13例，占76%，其中有2例在第二次行PET/CT检查时才检出原发灶；原发性肝癌2例，占12%；原发性贲门癌1例，占6%；原发性升结肠癌1例，占6%。在检查到原发灶的基础上，18F-FDG PET/CT亦发现10例合并转移者，其中合并肺转移者2例、合并淋巴结转移者3例、合并骨转移者2例及合并其他部位转移者3例，共发现病灶61处；2例肝癌患者单发脑转移灶中均有脑卒中。 结论 18F-FDG PET/CT在查找原发灶不明的脑转移瘤原发灶中有重要价值，并为临床分期及治疗提供有利帮助。

The value of 18F-FDG PET/CT in diagnosing brain metastases from unknown primary tumor

Objective To investigate the value of 18F-FDG PET/CT in diagnosis of brain metastases from unknown primary tumor. Method The 18F-FDG PET/CT findings of 17 patients with brain metastases from unknown primary tumor were retrospectively analyzed. Results Primary tumors of the seventeen cases were confirmed by biopsy, the accuracy rate was 100%. There were thirteen cases with primary lung cancer, accounted for 76%, including two cases of lung cancer which were found in the second PET/CT examination, two cases with liver cancer, accounted for 12%, one case with cardia cancer, accounted for 6%, one case with the ascending colon cancer, accounted for 6%. On the base of founding the primary tumor, 18F-FDG PET/CT also found 10 cases accompanied by lung metastasis(2 cases), lymph node metastases(3 cases), bone metastases(2 cases)and other sites of metastases(3 cases), a total of 61 lesions were detected. Two cases of liver cancer patients with single brain metastases had cerebral apoplexy. Conclusion 18F-FDG PET/CT contributes important value in finding brain metastases from unknown primary tumor, and is very helpful for clinical staging and treatment.