替米沙坦联合单硝酸异山梨酯治疗肺心病心力衰竭疗效观察

目的观察替米沙坦、单硝酸异山梨酯（ISMN）联合治疗重症肺心病心力衰竭的疗效。方法印例肺心病心力衰竭患者随机分为甲乙两组，每组30例。甲组（治疗组）在乙组常规治疗基础上加用替米沙坦、单硝酸异山梨酯，5d为1个疗程。结果治疗组显效率74．3％，总有效率为92．7％；对照组显效率为46．6％，总有效率为68．3％，两组显效率、总有效率差异均有统计学意义（均P〈0．01．）。结论替米沙坦、单硝酸异山梨酯（ISMN）合用治疗老年慢性肺源性心脏病心力衰竭疗效显著，不良反应少，使用安全。

Clinical observation of telmisartan and isosorbide mononltrate injection joint treatment on intensive pulmonary heart disease and heart failure

Objective To observe the effect of telmisartan and isosorbide mononitrate injection joint treat- ment on intensive pulmonary heart disease and heart failure. Methods 60 patients suffering from intensive pulmonary heart disease and heart failure were divided into observe group and control group randomly, patients in observe group were on the basis of the routine treatment given telmisartan and isosorbide mononitrate injection in 5 days period of treatment, while the control received only routine treatment, clinical effect of the two groups was observed and com-pared. Results Obvious effective rate was 74.3% and total effective rate was 92.7% which in control group were 46. 6% and 68. 3% ,respectively. There were significant difference in obvious effective rate and effective rates between the two groups(P <0.01). Conclusion The effect of telmisartan and isosorbide mononitrate injection joint treatment on intensive pulmonary heart disease and heart failure is excellent with less side-effects and safe medicament.