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The T-box transcription factor brachyury behaves as a tumor suppressor in gliomas |
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| Authors: | Filipe Pinto Ângela M Costa Gisele C Santos Marcus M Matsushita Sandra Costa Viviane AO Silva Vera Miranda-Gonçalves Celeste M Lopes Carlos A Clara Aline P Becker Luciano Neder Glaucia NM Hajj Isabela W da Cunha Chris Jones Raquel P Andrade Rui M Reis |
| Affiliation: | 1. Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Braga, Portugal ICVS/3B's – PT Government Associate Laboratory, Guimarães, Portugal I3S – Instituto de Investigação e Inovação em Saúde, University of Porto, Porto, Portugal Institute of Molecular Pathology and Immunology of the University of Porto – IPATIMUP, Porto, Portugal;2. Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Braga, Portugal ICVS/3B's – PT Government Associate Laboratory, Guimarães, Portugal I3S – Instituto de Investigação e Inovação em Saúde, University of Porto, Porto, Portugal;3. Department of Pathology, Barretos Cancer Hospital, São Paulo, Brazil;4. Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Braga, Portugal ICVS/3B's – PT Government Associate Laboratory, Guimarães, Portugal;5. Molecular Oncology Research Center, Barretos Cancer Hospital, São Paulo, Brazil;6. Center for Neuroscience and Cell Biology, University of Coimbra, Coimbra, Portugal Faculty of Pharmacy, University of Coimbra, Coimbra, Portugal;7. Neurosurgery Department, Barretos Cancer Hospital, Barretos, São Paulo, Brazil;8. Department of Pathology and Forensic Medicine, Faculty of Medicine of Ribeirão Preto, University of São Paulo (FMRP-USP), São Paulo, Brazil;9. International Research Center, AC Camargo Cancer Center, São Paulo, Brazil;10. Department of Molecular Diagnosis, Anatomic Pathology Department, AC Camargo Cancer Center, São Paulo, Brazil;11. Divisions of Molecular Pathology and Cancer Therapeutics, The Institute of Cancer Research (ICR), Sutton, UK;12. Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Braga, Portugal |
| Abstract: | |
| Keywords: | autophagy biomarker brachyury EMT glioblastoma gliomas prognosis TBXT tumor suppressor |