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Association Between Toll-Like Receptor 4 (TLR4) and Triggering Receptor Expressed on Myeloid Cells 2 (TREM2) Genetic Variants and Clinical Progression of Huntington's Disease
Authors:Romina Vuono PhD  Antonina Kouli MSc  Emilie M. Legault BSc  Lauriane Chagnon DEC  Kieren S. Allinson FRCPath  Alberto La Spada BSc  REGISTRY Investigators of the European Huntington's Disease Network  Ida Biunno PhD  Roger A. Barker MRCP  PhD  Janelle Drouin-Ouellet PhD
Affiliation:1. John van Geest Centre for Brain Repair & Department of Neurology, Department of Clinical Neurosciences, University of Cambridge, Cambridge, United Kingdom;2. Faculty of Pharmacy, University of Montreal, Montreal, Quebec, Canada;3. Department of Pathology, Cambridge University Hospitals NHS (National Health Service) Foundation Trust, Cambridge, United Kingdom;4. Integrated Systems Engineering, Milano, Italy;5. Institute for Genetic and Biomedical Research - CNR, Milano, Italy
Abstract:
Keywords:cognitive decline  Huntington  inflammation  motor symptoms  TLR4  TREM2
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