| 奥曲肽在肠梗阻治疗中的作用 |
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| 引用本文： | 许慕明,庄业忠,王伟峰,黄文河,黄棉生,吴俊东,李缪洋.奥曲肽在肠梗阻治疗中的作用[J].西部医学,2009,21(7):1171-1173. |
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| 作者姓名： | 许慕明 庄业忠 王伟峰 黄文河 黄棉生 吴俊东 李缪洋 |
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| 作者单位： | 汕头大学医学院附属肿瘤医院外科,广东,汕头,515041 |
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| 摘 要： | 目的探讨奥曲肽在肠梗阻治疗中的作用。方法将我科58例完全性肠梗阻患者随机分成对照组25例和治疗组33例。对照组采用常规治疗，治疗组除常规治疗外予奥曲肽（0．2mg，皮下注射，每8小时一次），对比两种方法的疗效。结果两组疗效差异有显著性。治疗组缓解率（完全缓解＋好转）为93．9％，对照组则为68％，缓解率差异有显著性；治疗组出现肛门排气时间比对照组早；能更好地纠正电解质失衡；治疗后的胃肠减压量比对照组明显减少，腹围减少比对照组明显。结论在常规治疗基础上应用奥曲肽治疗肠梗阻有良好的效果，适用于各型肠梗阻的治疗。
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| 关 键 词： | 奥曲肽 肠梗阻 疗效 |
Effects of octreotide in patients with bowel obstruction |
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| Institution: | XU Mu-ming, ZHUANG Ye-zhong, WANG Wei-feng, et al (Department of Surgery, The Affiliated Tumor Hospital of Shantou University Medical College, Shantou University Medical College, Shantou 515041, Guangdong , China) |
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| Abstract: | Objective To investigate the effects of octreotide in patients with bowel obstruction. Methods 58 patients with complete bowel obstruction were randomly divided into two groups, including control group （n= 25） and therapeutic group （n=33）. Control group was treated with traditional treatment, and therapeutic group with octreotide in combination with traditional treatment. The effects of the two treatments were compared. Results The effects of the two treatments were significantly different. Remission rate （CR＋PR） of therapeutic group was 93.9%, while that of control group 68%, which were significantly different. The exhaust of anus in therapeutic group was earlier than that of control group. The average volume of gastrointestinal decompression of therapeutic group was less than that of control group after treated. Conclusion Octreotide combination with traditional treatment can be very effective in the patients with different type of bowel obstruction. |
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| Keywords: | Octreotide Bowel obstruction Effect |
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