HLA-D typing in Austria. A panel study using 26 newly defined homozygous typing cells |
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Authors: | Agathe Haiek-Rosenmayr Gertraud Obergruber W R Mayr |
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Institution: | Institute for Blood Group Serology, University of Vienna. National Blood Group Reference Laboratory (WHO), National Tissue Typing Laboratory (Council of Europe) |
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Abstract: | A panel of 120 HLA-A, -B, -C and -DR typed Austrians has been typed for HLA-D by the use of 26 Homozygous Typing Cells (HTC). The new Austrian HTC, partly defined by the 9th International Histocompatibility Workshop (9WS), partly by a checkerboard experiment with internationally well defined reference HTC, type for HLA-Dw1 to -Dw7 and an obviously new, so far unknown HLA-DR2 related HLA-D determinant. Associations of HLA-DR and HLA-D antigens in Austria and their frequencies are determined. Antigen frequencies in Austria are compared to frequencies in other Caucasoid populations. |
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