| Is time to joint replacement a valid outcome measure in clinical trials of drugs for osteoarthritis? |
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| 引用本文： | Maillefert JF,Dougados M. Is time to joint replacement a valid outcome measure in clinical trials of drugs for osteoarthritis?[J]. Rheumatic Diseases Clinics of North America, 2003, 29(4): 831-845. DOI: 10.1016/S0889-857X(03)00057-7 |
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| 作者姓名： | Maillefert JF Dougados M |
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| 摘 要： |
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Is time to joint replacement a valid outcome measure in clinical trials of drugs for osteoarthritis? |
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| Maillefert Jean-Francis,Dougados Maxime. Is time to joint replacement a valid outcome measure in clinical trials of drugs for osteoarthritis?[J]. Rheumatic Diseases Clinics of North America, 2003, 29(4): 831-845. DOI: 10.1016/S0889-857X(03)00057-7 |
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| Authors: | Maillefert Jean-Francis Dougados Maxime |
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| Affiliation: | 1. Department of Rheumatology, Dijon University Hospital, 3 Rue du Fb Raines, 21000Dijon, France;2. INSERM ERIT-M 0207, Department of Rheumatology, University of Burgundy, Hôpital Général, 3 Rue du Fb Raines, 21000 Dijon, France;3. Institut de Rhumatologie, Assistance Publique-hôpitaux de Paris, René Descartes University, 27 Rue du Fb St Jacques, 75679 Paris, Cedex 14, France;1. DIME, Università degli Studi di of Genova, Genoa, Italy;2. Bavarian Center for Applied Energy Research (ZAE Bayern), Würzburg, Germany |
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| Abstract: | Each of the five sets of criteria for THA mentioned in this article should be regarded as preliminary. They require validation in future studies conducted in various cohorts of patients and in different countries. Moreover, a set of generally accepted criteria is badly needed. The number of proposed sets of criteria listed in this article indicates clearly that no consensus presently exists with respect to the optimal time for a patient who has hip OA to undergo THA. |
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