Granulocyte and Monocyte Adsorptive Apheresis for Ulcerative Colitis in a Patient with Low Bone Mineral Density Due to Fanconi-Bickel Syndrome |
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| Authors: | Makoto Tanaka Mayuko Nakanishi Hajime Miyazaki Ryuichi Morita Hiroki Eguchi Yoshiya Takeda Masanobu Katayama Motoo Tanaka Masamichi Bamba Tadashi Shigematsu |
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| Affiliation: | 1.Department of Gastroenterology and Hepatology, Saiseikai Shigaken Hospital, Imperial Gift Foundation Inc., Japan;2.Department of Diagnostic Pathology, Saiseikai Shigaken Hospital, Imperial Gift Foundation Inc., Japan |
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| Abstract: | Systemic steroid is required for the exacerbation of ulcerative colitis (UC), although its administration should be avoided in patients with a low bone mineral density (BMD) exacerbated by side effects of steroids. We herein report the successful induction of remission in an UC case with a low BMD due to Fanconi-Bickel syndrome-or glycogen storage disease type XI-using granulocyte and monocyte adsorptive apheresis (GMA). For a 43-year-old woman with a BMD of 50% the young adult mean, GMA was performed 2 times a week for a total of 10 times. GMA might be a steroid-free treatment option for UC patients with a low BMD. |
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| Keywords: | ulcerative colitis granulocyte and monocyte adsorptive apheresis bone density Fanconi-Bickel Syndrome |
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