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Patterns of Virus Exposure and Presumed Household Transmission among Persons with Coronavirus Disease,United States,January–April 2020
Authors:Rachel M Burke  Laura Calderwood  Marie E Killerby  Candace E Ashworth  Abby L Berns  Skyler Brennan  Jonathan M Bressler  Laurel Harduar Morano  Nathaniel M Lewis  Tiffanie M Markus  Suzanne M Newton  Jennifer S Read  Tamara Rissman  Joanne Taylor  Jacqueline E Tate  Claire M Midgley  for the COVID- Case Investigation Form Working Group
Abstract:We characterized common exposures reported by a convenience sample of 202 US patients with coronavirus disease during January–April 2020 and identified factors associated with presumed household transmission. The most commonly reported settings of known exposure were households and healthcare facilities; among case-patients who had known contact with a confirmed case-patient compared with those who did not, healthcare occupations were more common. Among case-patients without known contact, use of public transportation was more common. Within the household, presumed transmission was highest from older (>65 years) index case-patients and from children to parents, independent of index case-patient age. These findings may inform guidance for limiting transmission and emphasize the value of testing to identify community-acquired infections.
Keywords:2019 novel coronavirus disease  coronavirus disease  COVID-19  severe acute respiratory syndrome coronavirus 2  SARS-CoV-2  viruses  respiratory infections  zoonoses  household transmission  United States
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