NUT Carcinoma Arising from the Parotid Gland: A Case Report and Review of the Literature |
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| Authors: | Wei-Ning Saik Philip Da Forno Khin Thway Syed Ali Khurram |
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| Affiliation: | 1.Unit of Oral and Maxillofacial Pathology, School of Clinical Dentistry, 19 Claremont Crescent, Sheffield, S10 2TA UK ;2.Department of Histopathology, Leicester Royal Infirmary, University Hospitals of Leicester, Leicester, UK ;3.Head and Neck Unit; Sarcoma Unit, The Royal Marsden NHS Foundation Trust, London, UK |
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| Abstract: | NUT carcinoma is an aggressive carcinoma with an overall poor survival outcome. The mediastinum and head and neck area, especially the sinonasal region, are among the common sites of disease. Histopathological diagnosis of NUT carcinoma is often very challenging due to its overlapping features with other poorly differentiated carcinomas. We report a case of NUT carcinoma arising from the parotid gland of a young female patient. Primary NUT carcinoma of salivary gland is very rare, with only 15 such cases reported in the literature to date. Our case highlights the diagnostic challenges associated with such lesions. |
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| Keywords: | NUT carcinoma BRD4-NUT Parotid gland Salivary gland Poorly differentiated carcinoma Head and neck |
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