腹腔内感染的细菌谱及耐药性趋势探讨

目的了解我院近5年来腹腔内细菌感染的特点以及耐药趋势。方法对我院住院患者送检的843份腹水标本进行细菌培养鉴定及药敏试验。结果共检出阳性腹水标本86例,总共110株细菌,以革兰阴性菌为主(51.8%),其次是革兰阳性菌(48.1%)。其中大肠埃希菌占20.9%,葡菌球菌属占27.3%。药敏试验结果显示,革兰阴性菌中大肠埃希菌对氨苄西林、环丙沙星耐药率较高(80%以上),对亚胺培南敏感性最好,而革兰阳性菌对各类抗生素表现为多重耐药的特点,对万古霉素最为敏感。结论根据药敏试验结果合理选用抗生素以及采用联合用药,以减少新耐药株的出现。

Microbiological Analysis of Bacterial Peritonitis

Objective To analyze the bacterial characteristics of bacterial peritonitis in our hospital these five years.Methods A total of 843 ascites specimens from inpatients were cultured for further bacteria identification and drug resistance analysis.Results The main proportion of pathogenetic bacteria(51.8%) was gram-negative(E.coli accounting for 20.9%).The gram-positive bacteria were mainly staphylococci(27.3%).The result of drug resistance test indicated that susceptibility ratio of E.coli to ampicillin and ciprofloxacin was comparatively low(<20%) compared with imipenem.The charateristics of drug-resistence of gram-positive bacteria performed multiplicity,and it was most sensitive to vancomycin.Conclusion The antibiotics should be used reasonably by combination,which can reduce the development of drug-resistance.