新疆亚临床型克汀病流行病学调查报告

按照新疆ＩＤＤ流行与环境地理特征，沿山前丘陵河浴至河流下游冲积平原，对南疆喀什、巴州及北疆达板城等六个地区约３２７８名７－１４岁学龄儿童进行了全面系统的亚临床克汀病流调及临床检查。结果显示：南疆地区亚克汀 病流行强度为１４．５％，北、疆地区为５．２％，全疆平为９．１４％。

Epidemiological Investigation on Subclinical Cretinism in Xinjiang

According to the characteristic of epidemic of IDD in Xinjiangand geographical environment, along with piedmont hill valley to wash plain in area of lower reaches of rivers (non-endemic or milid-endemic areas),epidemiological investigation and clinical examination on subclinical cretinism were generally and systematically made in around 3 278schoolchildren at age of 7~ l4 in southern Xinjiang such as Kash, Bayngolin, etc. and northern Xinjiang, for example, Dabancheng, etc.,totally six areas. Results showed that epidemic intensities of subclinical cretinism were 14. 5 % in southern Xinjiang, and 5. 2% in northern Xinjiangrespectively, meanly 9. 14% in Xinjiang. It could be inferred from abovemention that there were 42. 36% hundred thousand patients with subclinical cretinism in Xinjiang. In this paper, geographical pathogeny of subclinical cretinism and endemic goiter was elaborated, and comparedthe endemic area with non-endemic area,psychomotor retardation, I131 absorbing function of thyroid, TRH stimulation test, TSH, F4, FT4,FT3, were also analysed by clinical epidemiology comprehensively. Analysis results were that the psychomotion test,TRH stimulation test and FT4 were much more sensitive and specific indices for diagnosing subclinical cretinism .