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颈必复颗粒抗炎镇痛作用的实验研究
引用本文:李东安,张艳铃,马杰,张慧颖,赵秀平. 颈必复颗粒抗炎镇痛作用的实验研究[J]. 中国中医药信息杂志, 2002, 9(12): 24-25,69
作者姓名:李东安  张艳铃  马杰  张慧颖  赵秀平
作者单位:辽宁省中医研究院,沈阳,110034
摘    要:目的:探讨颈必复颗粒的抗炎镇痛作用机理。方法:以皮下注射蛋清造成大鼠足跖肿胀,以二甲苯造成小鼠耳肿胀,以二甲苯造成小鼠耳廓毛细血管通透性增加,以大鼠皮下注射琼脂造成肉芽肿模型,以热板法和醋酸法造成小鼠疼痛模型,结果:颈必复颗粒对蛋清所致的大鼠足肿胀,二甲苯所致的小鼠耳肿胀,二甲苯所致的小鼠耳廓毛细管通透性增加,大鼠琼脂肉芽肿的生成均有显著的抑制作用,对热板所致小鼠疼痛和醋酸所致的小鼠扭体均有显著的抑制作用,结论:颈必复颗粒具有显著的抗炎,镇痛作用。

关 键 词:颈必复颗粒 抗炎 镇痛 实验研究 作用机理

Experimental Study on the Anti-inflammatory and Analyesia Actiosn of Jingbifu Granules
Li Dongan,Zhang Yanling,Ma Jie,et al. Experimental Study on the Anti-inflammatory and Analyesia Actiosn of Jingbifu Granules[J]. Chinese Journal of Information on Traditional Chinese Medicine, 2002, 9(12): 24-25,69
Authors:Li Dongan  Zhang Yanling  Ma Jie  et al
Abstract:objective: To study the anti-inflammatory and analyesia actions of Jingbifu granules. Methods: Causing inflammation in rats' feet by injecting egg white. Causing inflammation in mice's ears by dimethylbenzene. Causing the increasing of permeability of capillary in mice's ears by dimethylbenzene. Causing rats' granuloma by injecting agar in subcutaneous layer. Causing pain by hot plate and acetic acid. Results: Jingbifu granules has the inhibitory actions for inflammation in rats' feet causing by egg white and in mice's ears causing by dimethylbenzene, for the increasing of permeability of capillary in mice's ears by dimethylbenzene, for rats' granuloma by injecting agar, and for pain causing by hot plate and acetic acid. Conclusion: Jingbifu granules has notable actions of anti-inflammation and analyesia.
Keywords:Jingbifu granules  anti-inflammation  analyesia
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