Status and prospects of the treatment of disseminated germ-cell tumors

Summary Clinical investigation into the treatment of metastatic germ-cell tumors (GCT) has been highly successful. Future progress will depend on innovative approaches to identifying and preventing late drug toxicity, improving therapy for poor-risk patients, finding new drugs and therapies, and incorporating the findings of basic research into the clinical setting. This progress requires continued exchange of information among clinicians and laboratory investigators interested in these fascinating tumors.Supported in part by National Cancer Institute grants (CA-05826, CA-08748) and contracts (NO1-CM-57043), and a Junior Faculty Clinical Fellowship awarded to Dr. Bosl by the American Cancer Society