立体定向微创血肿抽吸术治疗少量丘脑出血的临床研究

目的: 分析立体定向微创血肿抽吸术治疗少量丘脑出血的可行性,并对其适应证进行初步探讨.方法: 出血量5～10 mL的少量丘脑出血患者22例,立体定向组10例,对照组12例.立体定向组患者常规行立体定向微创血肿抽吸术,术后12 h后根据情况反复给予尿激酶(1～2)万U血肿腔内注入,保留2～4 h后冲洗引流以便彻底清除血肿.两组患者均给予适当的对症治疗.所有患者均在治疗前以及治疗后14 d和30 d进行国立卫生研究院卒中量表(NIHSS)评分,分别计算各组治疗后14 d和30 d时的评分降低值(均与治疗前比较)并进行统计学分析.结果: 立体定向组14 d和30 d时的NIHSS评分降低值显著高于对照组,表明立体定向微创血肿抽吸术后患者神经功能恢复更快.结论:立体定向微创血肿抽吸术可显著改善少量丘脑出血患者的转归.

Stereotactic Minimally Invasive Aspiration for Small Thalamic Hemorrhage A Clinical Study

Objective:To explore the feasibilitv of stereotactic minimally invasive aspiration of small thalamic bemorrhage.Methods:Twenty-two patients with small thalamic hemowhage(5 to 10 mL)were divided into two groups:a stereotactic group(n=10)and a control group(n= 12).The patients in the stereotactic group received stereomctic minimally invasive puncture and drainage of hematomas.According to the condition,repeated infusion of urokinase(10-20 kU) into the hematoma cavities were administered 12 hours after the procedure,and the hematomas were irrigated and drained so as to removal of them completely after retaining for 2-4 hours, The appropriate symptomatic treatment was administered in the patients in both groups.National Institutes of Health Stroke Scale(NIHSS)scores were determined 14 and 30 days before and after the treatment in all the patients.The reductiom of the NIJSS scores (as compared with those before treatment)were calculated at day 14 and 30 respectively after the treatment. Results:The reductiom of the NIHSS scores in the stereotactic group at day 14 and 30 were significantly higher than those in the control group.It was suggested that the neurological functional recovery of the patients was faster after stereotmtic minimally invasive puncture and drainage of intracranial hematorna in the stereotactic group.Concision:The stereotactic minimally invasive puncture and drainage of intracranial hematoma may significantly improve the outcome in patients with small thalamic hemorrhage.