| 高效液相色谱法测定救尔心胶囊中原儿茶醛含量 |
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| 引用本文： | 付凌燕,李亚荣.高效液相色谱法测定救尔心胶囊中原儿茶醛含量[J].中国药业,2010,19(15):30-31. |
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| 作者姓名： | 付凌燕 李亚荣 |
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| 作者单位： | 吉林省吉林市食品药品检验所,吉林,吉林,132001 |
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| 摘 要： | 目的建立测定救尔心胶囊中原儿茶醛含量的方法。方法采用高效液相色谱法,色谱柱为Phenomenex C18柱（250mm×4.6mm,5μm）,流动相为甲醇-1%醋酸溶液（12：88）,流速0.8mL/min,检测波长279nm,柱温24℃。结果原儿茶醛质量浓度在1.998～19.980μg/mL范围内与峰面积线性关系良好,r=1.0000;平均加样回收率为98.94%,RSD=0.97%（n=6）。结论所用方法简便易行,结果准确可靠,适用于救尔心胶囊的质量控制。
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| 关 键 词： | 高效液相色谱法 救尔心胶囊 原儿茶醛 含量测定 |
Determination of Protocaechuic Aldehyde in Jiuerxin Capsules by HPLC |
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| Fu Lingyan,Li Yarong.Determination of Protocaechuic Aldehyde in Jiuerxin Capsules by HPLC[J].China Pharmaceuticals,2010,19(15):30-31. |
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| Authors: | Fu Lingyan Li Yarong |
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| Institution: | (Jilin Institute for Food and Drug Control,Jilin,Jilin,China 132001) |
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| Abstract: | Objective To set up a method for the quality control of Jiuerxin Capsules.Methods The HPLC method was developed to quantitative determination.The Phenomenex C18 column（250 mm × 4.6 mm,5 μm） was used.The mobile phase was methanol-1% acetic acid（12：88）.The column temperature was 24 ℃,the detection wavelength was 279 nm,the flow rate was 0.8 mL /min.Results The linear range of protocaechuic aldehyde was 1.998-19.980 μg /mL（r = 1.000 0）.The average recovery rate was 98.94%,and RSD was 0.97%（n = 6）.Conclusion The method is simple,accurate and suitable for the quality control of Jiuerxin Capsules |
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| Keywords: | HPLC Jiuerxin Capsules protocaechuic aldehyde content determination |
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