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托烷司琼预防剖宫产术后恶心呕吐的临床效果观察
引用本文:冯国良,何志恩,冯超群,欧阳玉琼.托烷司琼预防剖宫产术后恶心呕吐的临床效果观察[J].现代医药卫生,2011,27(10):1469-1471.
作者姓名:冯国良  何志恩  冯超群  欧阳玉琼
作者单位:佛山市顺德区均安医院麻醉科,广东,顺德,528329
摘    要:目的:观察静脉注射托烷司琼对剖宫产术后恶心呕吐的影响.方法:90例腰硬麻醉的剖宫产病人,ASA Ⅰ~Ⅱ级,随机分为对照组(A组)、恩丹西酮组(B组)和托烷司琼组(C组),每组30例.手术结束时A、B、C 3组分别静脉注射生理盐水5 mL、恩丹西酮8 mg、托烷司琼3 mg.观察每例病人用药前、用药后10 min和30 min的血压、心率与术后12、24和48 h内恶心呕吐发生率,同时记录用药后眩晕、皮疹、腹部不适等并发症.结果:注射药物前后3组病人血压和心率,及眩晕、皮疹、腹部不适等变化差异无显著性(P>0.05);B组和C组恶心呕吐的发生率明显低于A组(P<0.05);与B组比较,C组恶心呕吐发生率下降显著(P<0.05).结论:静脉注射恩丹西酮和托烷司琼对循环功能无影响,用药后不良反应少,均可安全有效地应用于临床;恩丹西酮和托烷司琼均可降低剖宫产术后恶心呕吐的发生率,托烷司琼的作用优于恩丹西酮.

关 键 词:托烷司琼  恩丹西酮  剖宫产  恶心呕吐

Effects observation of tropisetron on preventing PONV after cesarean section
FENG Guo-liang , HE Zhi-en , FENG Chao-qun , OUYANG Yu-qiong.Effects observation of tropisetron on preventing PONV after cesarean section[J].Modern Medicine Health,2011,27(10):1469-1471.
Authors:FENG Guo-liang  HE Zhi-en  FENG Chao-qun  OUYANG Yu-qiong
Institution:FENG Guo-liang,HE Zhi-en,FENG Chao-qun,OUYANG Yu-qiong(Department of Anesthesiology,Jun′ an Hospital of Shunde District,Foshan,Guangdong 528329,China)
Abstract:Objective:To study the effects of tropisetron on postoperative nausea and vomiting(PONV) after cesarean section.Methods:90 cases of spinal and epidural anesthesia,ASA score I-II,scheduled for cesarean section,were randomly and evenly allocated into three groups: normal saline study group(group A),ondanstron group(group B) and tropisetron group(group C).Normal saline,ondanstron and tropisetron were intravenously given to the patients after cesarean section respectively.The change of BP and HR at 10,30 min be...
Keywords:Tropisetron  Ondanstron  Cesarean section  Vomiting and nausea  
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