Severe endothelial injury and subsequent repair in patients after successful cardiopulmonary resuscitation |
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| Authors: | Katrin Fink Meike Schwarz Linda Feldbrügge Julia N Sunkomat Tilmann Schwab Natascha Bourgeois Manfred Olschewski Constantin von zur Mühlen Christoph Bode Hans-Jörg Busch |
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| Affiliation: | (1) Department of Cardiology and Angiology, University hospital of Freiburg, Hugstetter Str. 55, 79106 Freiburg im Breisgau, Germany;(2) Department for Biometry and Statistics, University of Freiburg, Stefan-Meier-Str. 26, 79104 Freiburg im Breisgau, Germany |
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| Abstract: | Introduction Ischemia and reperfusion after cardiopulmonary resuscitation (CPR) induce endothelial activation and systemic inflammatory response, resulting in post-resuscitation disease. In this study we analyzed direct markers of endothelial injury, circulating endothelial cells (CECs) and endothelial microparticles (EMPs), and endothelial progenitor cells (EPCs) as a marker of endothelial repair in patients after CPR. |
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