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促血管生成素-1与血管通透性调节
引用本文:乐飞,金惠铭. 促血管生成素-1与血管通透性调节[J]. 中国病理生理杂志, 2004, 20(10): 1929-1932
作者姓名:乐飞  金惠铭
作者单位:复旦大学上海医学院生理与病理生理学系,上海 200032
摘    要:Angiopoietin-1 (Ang-1) is a newly-found endothelium-specific proangiogenic factor and it had been proved essential roles in both vasculogenesis and angiogensis. Among them, its anti - leakage abihty may have great potential apphcations in chnical treatment of vascular hyper-permeability in a variety of diseases such as cancer, diabetic retinopathy, rheumatoid arthritis, asthma. In this review, some research progresses focused on this aspect are discussed.

关 键 词:血管生成素  内皮细胞  毛细血管通透性  
文章编号:1000-4718(2004)10-1929-04
收稿时间:2003-02-26
修稿时间:2003-05-05

Angiopoietin-1 and regulation of vascular permeability
YUE Fei,JIN Hui-ming. Angiopoietin-1 and regulation of vascular permeability[J]. Chinese Journal of Pathophysiology, 2004, 20(10): 1929-1932
Authors:YUE Fei  JIN Hui-ming
Affiliation:Department of Physiology & Pathophysiology, Fudan University Shanghai Medical College, Shanghai 200032, China
Abstract:Angiopoietin-1 (Ang-1) is a newly-found endothelium-specific proangiogenic factor and it had been proved essential roles in both vasculogenesis and angiogensis. Among them, its anti-leakage ability may have great potential applications in clinical treatment of vascular hyper-permeability in a variety of diseases such as cancer, diabetic retinopathy, rheumatoid arthritis, asthma. In this review, some research progresses focused on this aspect are discussed. [
Keywords:Angiopoietin  Endothelial cells  Capillary permeability
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