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Drug Utilisation Study in a Tertiary Care Center: Recommendations for Improving Hospital Drug Dispensing Policies
Authors:Niti Mittal  R. Mittal  I. Singh  Nusrat Shafiq  S. Malhotra
Affiliation:Department of Pharmacology, Pt. B. D. Sharma Postgraduate Institute of Medical Sciences (PGIMS), Rohtak-124 001, India;1.Department of Pharmacology, Postgraduate Institute of Medical Education and Research (PGIMER), Sector 12, Chandigarh-160 012, India
Abstract:Drug therapy accounts for a major portion of health expenditure. A useful strategy for achieving cost efficient healthcare is drug utilisation research as it forms the basis for making amendments in drug policies and helps in rational drug use. The present observational study was conducted to generate data on drug utilization in inpatients of our tertiary care hospital to identify potential targets for improving drug prescribing patterns. Data was collected retrospectively from randomly selected 231 medical records of patients admitted in various wards of the hospital. WHO Anatomical Therapeutic Chemical/Defined Daily Dose methodology was used to assess drug utilisation data and drug prescriptions were analysed by WHO core drug indicators. Antibiotics were prescribed most frequently and also accounted for majority of drug costs. The prescribed daily dose for most of the antibiotics corresponded to defined daily dose reflecting adherence to international recommendations. Brand name prescribing and polypharmacy was very common.78% of the total drugs prescribed were from the National List of Essential Medicines 2003. Restricting the use of newer and costlier antibiotics, branded drugs and number of drugs per prescription could be considered as targets to cut down the cost of drug therapysignificantly.
Keywords:Drug utilisation   Defined daily dose   Prescribed daily dose   Polypharmacy   Essential medicines
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