临床药师主导药学路径服务模式对脑梗死住院患者用药的影响

目的探讨临床药师主导的药学路径服务模式对脑梗死患者住院期间用药情况的影响。方法选取医院2017年6月至2018年11月收治的脑梗死患者109例,按随机数字表法分为对照组(54例)和研究组(55例)。两组患者均予基础治疗,对照组患者予常规医疗服务,研究组患者予临床药师主导药学路径的药学服务。比较两组患者的临床疗效、不合理用药水平、药品不良反应发生率、患者对药学服务的满意度,并对患者出院后1个月的用药依从性进行随访。结果研究组总有效率为94.55%,明显高于对照组的79.63%(P<0.05);研究组用药医嘱不合理率为1.40%,明显低于对照组的2.44%(P<0.05);研究组患者对药学服务的满意度为94.55%,明显高于对照组的79.63%(P<0.05);研究组患者药品不良反应发生率为7.27%,明显低于对照组的18.52%(P<0.05);研究组患者用药依从率为94.55%,明显高于对照组的77.78%(P<0.05)。结论临床药师主导的药学路径服务模式用于脑梗死的治疗有积极作用,可提高临床疗效,降低不合理用药水平及药品不良反应发生率,提高患者对用药服务的满意度和用药依从性。

Effect of Clinical Pharmacist-Led Pharmaceutical Pathway Service Mode on Drug Use in Patients with Cerebral Infarction During Hospitalization

Objective To explore the effect of clinical pharmacist-led pharmaceutical pathway service mode on drug use in patients with cerebral infarction during hospitalization.Methods A total of 109 patients with cerebral infarction admitted to the hospital from June 2017 to November 2018 were selected and divided into the control group(54 cases)and research group(55 cases)according to random number table method.The control group was given routine medical services,while the research group was provided clinical pharmacists with pharmaceutical services leading the pharmaceutical pathway.The effect of drug use,unreasonable drug use level,incidence of adverse drug reactions and patients’satisfaction rate with pharmaceutical service during hospitalization were compared between the two groups.A follow-up study was conducted on the drug compliance of the patients one month after discharge.Results The total effective rate in the research group was 94.55%,which was significantly higher than 79.63%in the control group(P<0.05);the unreasonable rate of use orders in the research group was 1.40%,which was significantly lower than 2.44%in the control group(P<0.05);the satisfaction rate of the patients in the research group with pharmaceutical services was 94.55%,which was significantly higher than 79.63%in the control group(P<0.05);the incidence of adverse drug reactions in the research group was 7.27%,which was significantly lower than 18.52%in the control group(P<0.05);the compliance rate in the research group was 94.55%,which was significantly higher than 77.78%in the control group(P<0.05).Conclusion The service mode of clinical pharmacist-led pharmaceutical pathway plays a positive role in the treatment of cerebral infarction patients.It can improve the efficacy of medication,reduce the level of unreasonable drug use and the incidence of adverse drug reactions,improve the satisfaction of patients with medication services,and enhance the compliance of patients with medication.