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Pregnancy in a Patient With Chronic Thromboembolic Pulmonary Hypertension After Successful Treatment with Balloon Pulmonary Angioplasty
Affiliation:1. Physics Department and International Laser Center, M.V. Lomonosov Moscow State University, Leninskye Gory 1, Moscow 119991, Russia;2. Department of Computational Mathematics and Cybernetics, M.V. Lomonosov Moscow State University, Leninskye Gory 1, Moscow 119991, Russia;1. Department of Cardiovascular, Respiratory, Nephrologic, Anesthesiologic and Geriatric Sciences, Sapienza University of Rome, Rome, Italy;2. Department of Respiratory Diseases, S. Camillo-Forlanini Hospital, Rome, Italy;3. Department of Medico-Surgical Sciences and Biotechnologies, Sapienza University of Rome, Latina, Italy;4. Department of Thoracic Surgery, Policlinico Umberto I, Sapienza University of Rome, Rome, Italy;5. Radiology Unit, S. Camillo-Forlanini Hospital, Rome, Italy;6. Department of AngioCardioNeurology, Neuromed, Pozzilli, Isernia, Italy;1. The International Society for Heart and Lung Transplantation Transplant Registry, Dallas, Texas;2. Division of Cardiovascular Medicine, University of Utah School of Medicine, Salt Lake City, Utah;3. Division of Cardiovascular Medicine, Brigham and Women’s Hospital Heart and Vascular Center, Harvard University, Boston, Massachusetts;4. Division of Pediatrics, Immunology and Pulmonary Medicine, Washington University in St. Louis, St. Louis Children’s Hospital, St. Louis, Missouri;5. Division of Cardiothoracic Surgery, University of Alabama, Birmingham, Alabama;6. Division of Thoracic Surgery and Division of Pediatric Cardiology, University of Toronto, Toronto, Ontario, Canada;7. Division of Pediatric Cardiology, Freeman Hospital, Newcastle Upon Tyne, United Kingdom;8. Department of Thoracic Surgery, University Hospital Gasthuisberg, Leuven, Belgium;9. Division of Thoracic Surgery, Hospital Universitario Fundación Favaloro, Buenos Aires, Argentina;10. Division of Cardiac Surgery, Hospital De Messejana, Fortaleza, Ceará, Brazil;11. Division of Cardiology, Fundación Cardioinfantil—Instituto de Cardiología, Bogota, Colombia;12. Division of Cardiology, Heart and Lung Transplant Program, Bologna University Hospital, Bologna, Italy;13. Department of Cardiovascular Surgery, Heart Centre, Ankara University School of Medicine, Ankara, Turkey;14. Department of Pediatrics, Surgery and Immunology, Alberta Transplant Institute, University of Alberta, Edmonton, Alberta, Canada;15. Department of Cardiac Surgery, Medical University of Vienna, Vienna, Austria;p. Division of Cardiovascular Surgery, King Faisal Specialist Hospital & Research Center, Riyadh, Saudi Arabia;q. Division of Cardiothoracic Surgery, Florida Hospital, Orlando, Florida;r. Department of Cardiac Surgery, University Heart Centre Hamburg, Hamburg, Germany;1. Department of Cardiology, Tokyo Women’s Medical University, Tokyo, Japan;2. Clinical Research Division for Heart Rhythm Management Department of Cardiology, Tokyo Women’s Medical University, Tokyo, Japan
Abstract:Pulmonary hypertension has been recognized as a contraindication to pregnancy. Recently, several groups have shown promising results with the use of balloon pulmonary angioplasty (BPA) in the treatment of chronic thromboembolic pulmonary hypertension (CTEPH) patients with distally located organized thrombi who were not candidates for pulmonary endarterectomy. We present the case report of a 26-year-old woman who became pregnant after successful treatment of severe CTEPH with the use of BPA. We conclude that patients undergoing effective BPA for CTEPH can consider becoming pregnant if followed closely by a multidisciplinary team, including experts in thrombosis, pulmonary hypertension, and obstetrics.
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