Botulinum toxin type-A injection to treat patients with intractable anismus unresponsive to simple biofeedback training |
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Authors: | Yong Zhang Zhen-Ning Wang Lei He Ge Gao Qing Zhai Zhi-Tao Yin Xian-Dong Zeng |
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Institution: | Yong Zhang, Lei He, Ge Gao, Qing Zhai, Zhi-Tao Yin, Xian-Dong Zeng, Department of Constipation and Pelvic Floor Disease, Constipation Treatment Center, Shenyang Coloproctology Hospital, Shenyang 110002, Liaoning Province, ChinaYong Zhang, Zhen-Ning Wang, Department of Oncology, No. 1 Hospital of China Medical University, Shenyang 110001, Liaoning Province, China |
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Abstract: | AIM: To evaluate the efficacy of botulinum toxin type A injection to the puborectalis and external sphincter muscle in the treatment of patients with anismus unresponsive to simple biofeedback training.METHODS: This retrospective study included 31 patients suffering from anismus who were unresponsive to simple biofeedback training. Diagnosis was made by anorectal manometry, balloon expulsion test, surface electromyography of the pelvic floor muscle, and defecography. Patients were given botulinum toxin type A (BTX-A) injection and pelvic floor biofeedback training. Follow-up was conducted before the paper was written. Improvement was evaluated using the chronic constipation scoring system.RESULTS: BTX-A injection combined with pelvic floor biofeedback training achieved success in 24 patients, with 23 maintaining persistent satisfaction during a mean period of 8.4 mo.CONCLUSION: BTX-A injection combined with pelvic floor biofeedback training seems to be successful for intractable anismus. |
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Keywords: | Constipation Anismus Biofeedback training Obstructed outlet constipation |
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