基于文献报道的女性冠心病辨证构成研究

揭示女性冠心病辨证构成特征,为中医防治女性冠心病及中药新药研发提供参考。方法 收集期刊文献数据库中近15年具有明确诊疗记录的冠心病病例报道,提取性别、年龄、中医证候和病性进行整理。分别统计分析男性、女性和女性不同年龄段冠心病患者中医证候、病性分布情况,并进行比较分析。结果 女性患者中气虚血瘀证居首位,其次为胸阳不振、气阴两虚、肝肾阴虚、心血瘀阻、气滞血瘀;病性依次为血瘀、气虚、阴虚、气滞;其中49岁以下患者中居前列的是气滞血瘀、气滞心胸、胸阳不振和心血瘀阻,病性以气滞、血瘀为主;49～60岁中肝肾阴虚出现最多,病性以阴虚为首;60岁以上患者中以气虚血瘀、气阴两虚为首,病性主要为血瘀、气虚。男性患者以痰瘀互结证为主,血瘀、气滞居病性前2位。结论 冠心病中医辨证构成存在性别差异,女性患者辨证构成存在自身特征,不同年龄段的女性患者辨证构成不同。

Literature Research on Syndrome Differentiation Component of Coronary Heart Disease for Women

Objective To reveal the characteristics of syndrome differentiation of female coronary heart disease (CHD), and to provide reference for the prevention and treatment of CHD in TCM and the research and development of new Traditional Chinese Medicine (TCM) drugs. Methods The reports of CHD cases with definite diagnosis and treatment records in recent 15 years were collected and sorted out by gender, age, TCM Syndrome and the nature of disease. The distribution of TCM syndromes and diseases of CHD in Male, female and female patients of different ages were analyzed statistically. Results Qi deficiency and blood stasis Syndrome was the first in female patients, followed by chest-yang depression, qi-yin deficiency, liver-kidney Yin deficiency, heart-blood stasis, Qi stagnation and blood stasis the nature of disease were blood stasis, Qi deficiency, Yin deficiency and Qi stagnation Among the patients under 49 years old, Qi stagnation and blood stasis, Qi stagnation, chest-yang depression and heart-blood stasis were the most common, and Qi stagnation and blood stasis were the main nature of disease while Yin deficiency of liver and kidney was the most common in 49 ~ 60 years old, and the Yin deficiency was the most common nature of disease. Over 60 years old in patients with Qi Deficiency blood stasis, Qi and Yin deficiency is the first, and the main nature of disease were blood stasis, Qi deficiency. In male patients, phlegm-blood stasis was the main syndromes, blood stasis and qi stagnation were the top two. Conclusion The Constitution of TCM syndrome differentiation of CHD has sex difference, the constitution of syndrome differentiation of female patients has its own characteristics, and the constitution of syndrome differentiation of female patients in different age groups is different.