原发性肺癌病理及病灶位置与中医证候相关性的回顾性研究

目的 从肺癌病理类型、原发灶位置及肺癌转移灶位置与中医证候的相关性进行回顾性探讨。方法 采用回顾性研究方法，对原发性肺癌病例共计185例数据进行分析研究，主要对肺癌病理类型、原发灶位置及转移灶位置与中医证候等进行卡方检验分析。结果 肺腺癌出现痰热郁肺证的几率（概率）更大，而出现肺脾气虚证的几率较小，差异均具有统计学意义（P＜0.05）；肺癌原发灶在右侧者较在左侧者有更多表现为痰热郁肺证的趋势，但差异不具有统计学意义（P＞0.05）；肺癌合并心包转移与气虚血瘀证之间表现出正相关趋势，差异无统计学意义（P＞0.05）；肺癌合并脑转移与肺脾气虚证之间表现出正相关，差异具有统计学意义（P＜0.05）。结论 原发性肺癌的病理类型、病灶位置与中医证候具有一定相关性，通过证型研究对肺癌合并转移有临床提示作用。

Retrospective Study on the Correlation between Pathology and Lesion Locationof Primary Lung Cancer and TCM Syndromes

Objective In this retrospective study, the correlation between pathological type, primary lesion location and metastatic lesion of lung cancer and TCM syndromes was studied. Methods A retrospective study was conducted to analyze the data of 185 cases of primary lung cancer,and Chi-square test was performed on the pathological type, primary lesion location, metastatic lesion location and TCM syndromes of those cases. Results Lung adenocarcinoma is more likely to have phlegm heat stagnation lung syndrome, but less likely to have lung Qi deficiency syndrome, the differences are statistically significant. The primary tumor of lung cancer showed more tendency of phlegm-heat stagnation lung syndrome in the right side than in the left side, but the difference was not statistically significant .There was a positive correlation trend between lung cancer with pericardial metastasis and Qi deficiency and blood stasis syndrome, and the difference was not statistically significant .There was a positive correlation between primary lung cancer with brain metastasis and lung Qi deficiency syndrome, and the difference was statistically significant. Conclusion The pathological type and location of primary lung cancer have certain correlation with TCM syndromes. The syndrome type has a clinical suggestive effect on lung cancer combined with metastasis.