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Phase 1 study of the combination of vemurafenib,carboplatin, and paclitaxel in patients with BRAF-mutated melanoma and other advanced malignancies
Authors:Minny Bhatty PhD  Shumei Kato MD  Sarina A. Piha-Paul MD  Aung Naing MD  Vivek Subbiah MD  Helen J. Huang MD  MS  Daniel D. Karp MD  Apostolia M. Tsimberidou MD  PhD  Ralph G. Zinner MD  Wen-Jen Hwu MD  PhD  Milind Javle MD  Sapna P. Patel MD  Mimi I. Hu MD  Gauri R. Varadhachary MD  Anthony P. Conley MD  Nishma M. Ramzanali MS  CCRP  Veronica R. Holley  Razelle Kurzrock MD  Funda Meric-Bernstam MD  Young Kwang Chae MD  Kevin B. Kim MD  Gerald S. Falchook MD  Filip Janku MD  PhD
Affiliation:1. Department of Investigational Cancer Therapeutics (Phase I Clinical Trials Program), Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas;2. Division of Hematology and Oncology, University of California San Diego Moores Cancer Center, San Diego, California;3. Thomas Jefferson University, Philadelphia, Pennsylvania;4. Department of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas;5. Department of Gastrointestinal Medical Oncology, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas;6. Department of Endocrine Neoplasia and Hormonal Disorders, The University of Texas MD Anderson Cancer Center, Houston, Texas;7. Department of Sarcoma Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas;8. Developmental Therapeutics, Lurie Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, Illinois

Division of Hematology Oncology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois;9. California Pacific Medical Center Research Institute, San Francisco, California;10. Sarah Cannon Research Institute at Health ONE, Denver, Colorado

Abstract:
Keywords:BRAF mutation  carboplatin  paclitaxel  vemurafenib
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