| 替普瑞酮对幽门螺杆菌和氨基己糖作用的临床研究 |
| |
| 引用本文： | 董秀云,叶嗣懋,林三仁,陈寿坡,刘新光,贾博琦. 替普瑞酮对幽门螺杆菌和氨基己糖作用的临床研究[J]. 北京大学学报(医学版), 1997, 0(5) |
| |
| 作者姓名： | 董秀云 叶嗣懋 林三仁 陈寿坡 刘新光 贾博琦 |
| |
| 作者单位： | 北京医科大学第三医院消化科!100083(董秀云，叶嗣懋，林三仁)，北京协和医科大学(陈寿坡)，北京医科大学第一医院(刘新光，贾博琦) |
| |
| 摘 要： | 目的：观察胃粘膜保护剂替普瑞酮、麦滋林对胃粘膜幽门螺杆菌（Hp）感染和粘膜防御能力的作用。方法：用比色的方法测胃粘膜氨基已糖含量，用W－S银染色法检查Hp，观察1993年～1994年中收治的慢性浅表性胃炎患者。结果：替普瑞酮增加Hp阴性（18±5）mg／g和阳性（16±4）mg／g病人的胃粘膜氨基已糖含量；安滋林组治疗前后氨基已糖无明显增加。替普瑞酮、麦滋林抑制Hp，有效抑制率分别为76．92％和77．78％，两者无显著差异（P＜0．05）。结论：替普瑞酮和安滋林抑制Hp的生长，这种抑制作用似乎和氨基已糖的增加关系不十分密切。
|
| 关 键 词： | 胃粘膜 螺杆菌.幽门 螺杆菌感染／药物疗法 氨基己糖 替普瑞酮 |
EFFECTS OF TEPRENONE ON H.PYLORI AND HEXOSAMINE:A CLINICAL STUDY |
| |
| DONG Xiuyun, YE Simao, LIN Sanren. EFFECTS OF TEPRENONE ON H.PYLORI AND HEXOSAMINE:A CLINICAL STUDY[J]. Journal of Peking University. Health sciences, 1997, 0(5) |
| |
| Authors: | DONG Xiuyun YE Simao LIN Sanren |
| |
| Abstract: | Objective: To observe the effects of Teprenone and Marzulene-s on H. Pyori infection and the gastric mucosal contents of Hexasamine (Hex). Methods: H. Pylori was examined by W-S stain before and after treatment. Determination of Hex was performed by colorimetry. The study included patients with endoscopically proven gastritis. Results: 1. The Hex level was increased by Trprenone in H. Pylori negative and positive groups. 2. H. pylori was inhibited in Teprenone and Marzulene-s groups. The inhibiting ratio was 76. 92 % and 77. 78 % respectively. But there was no significant difference between these two groups.Conclusion: H. Pylori was inhibited by Teprenone and Marzulene-s. The effect may not correlated to the Hex. |
| |
| Keywords: | Gastric mucosa Helicobacter pylori Helicobacter infections/drug ther Hexosamine Teprenone |
| 本文献已被 CNKI 等数据库收录！ |
