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Dermaprotecting properties of sodium succinate under conditions of impaired circulation
Authors:P A Galenko-Yaróshevskii  I S Chekman  O S Medvedev  V I Kondratyuk  K S Vas'kov  A V Uvarov  S E Gumenyuk  V N Kovalenko  P B Popov  V L Popkov
Institution:(1) Department of Pharmacology, Kuban' State Medical Academy, Krasnodar;(2) Department of Pharmacology, Ukrainian National Medical University, Kiev;(3) Laboratory of Pharmacology, Cardiology Research-and-Production Center, Ministry of Health, Moscow
Abstract:Sodium succinate improves the survival of a skin graft in mice, rats, and dogs normalizes histamine and serotonin concentrations in the epidermis and blood, exhibits antitoxic activity, improves microcirculation in the skin, brain, heart, kidneys, and testes without any appreciable effect on systemic arterial pressure, cardiac function, and liver blood flow in rats. Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 126, No. 10, pp. 420–424, October, 1998
Keywords:sodium succinate                      dermaprotecting activity                      microcirculation
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