吸入噻托溴铵治疗慢性阻塞性肺疾病40例肺功能观察

目的:探讨吸入噻托溴铵治疗稳定期慢性阻塞性肺疾病(COPD)的疗效。方法:将80例稳定期COPD患者随机分为两组,对照组仅给予常规治疗;治疗组在常规治疗的基础上加吸噻托溴铵。分别于治疗前、治疗3月后测定两组患者的肺功能,观察两组患者肺功能和临床症状的改善情况。结果:治疗组FEV1%、FEV1、PEF、FEV1/FVC、V50、V25、Raw较治疗前明显改善(P<0.05);肺功能及临床症状改善明显好于对照组(P<0.05)。结论:COPD患者吸入噻托溴铵可明显改善肺功能和临床症状。

Clinical observation of inhaling tiotropium Bromide in 40 patients with COPD

Objective：To evaluate the clinical effects of inhaling tiotropium bromide in patients with stable COPD.Methods：80 patients were divided into 2 groups randomly： conventional treatment was given to 40 patients as control group,tiotropium bromide was inhaled by another 40 patients as treated group together with conventional treatment.Then the lung function test was measured after and before given those drugs in 2 groups.Results：The FEV1%、FEV1、PEF、FEV1/FVC、V50、V25、Raw were markedly improved in the treated group.The improvement of the lung functions were significantly greater in treated group than that in control group.And the clinical symptoms were also improved as well as the lung functions.Conclusion：The lung function and clinical symptoms of COPD can be evidently improved by inhaling tiotropium bromide.It is maybe a recommended treatment for the stable COPD.