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Paludisme sévère de l'enfant au Togo
Authors:JK Assimadi,AD Gbadoé  ,DY Atakouma,K Agbé  nowossi,K Lawson-Evi,A Gayibor,Y Kassankogno
Affiliation:1Service de pédiatrie, CHU-Tokoin, BP 57, Lomé, Togo, France;2Service national du paludisme, BP 518, Lomé, Togo, France;3Bureau AFRO/OMS, lutte contre le paludisme, centre OMS, BP 1504, Lomé, Togo, France
Abstract:

Background

The definition of severe malaria is no longer limited to cerebral malaria, but is as well extended to other clinical forms of the disease. This work analyses epidemiological, clinical and evolutive aspects of severe malaria in Togo.

Patients and methods

This study included 549 children, aged from O to 15 years, hospitalized in 1994–5 in the pediatric department of the Lome-Tokoin University Teaching Hospital for severe malaria as defined by World Health Organization (WHO) criteria.

Results

The hospitalization frequency was 7.44%; the maximum frequency was from 1 to 5 years of age, but 6.56% of patients were more than 10 years old The most frequent clinical form was that of severe anemia, fallowed by cerebral complications, as seen in many African countries. The death rate was 18.94% and the proportional mortality was 8.21%; 2.73% of the patients had neurological sequelae (behaviour disturbances in five cases, aphasia in four, hemiplegia in three, munchment in one, oculomotor paralysis in one, and cerebellar ataxia in one). Hypoglycemia was fairly frequent (11.6%) and was associated with a poor prognosis.

Conclusion

It is possible to improve severe malaria prognosis in Africa by insisting not only on better equipment in intensive care wards, but also on improved and early management of hypoglycemia.
Keywords:Author Keywords: paludisme   hypoglycé  mie   Togo
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