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The Lymph Node Ratio Is a Powerful Prognostic Factor of Node-Positive Colon Cancers Undergoing Potentially Curative Surgery |
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| Authors: | Gennaro Galizia Michele Orditura Francesca Ferraraccio Paolo Castellano Margherita Pinto Anna Zamboli Sabrina Cecere Ferdinando De Vita Carlo Pignatelli Eva Lieto |
| Affiliation: | (1) Division of Surgical Oncology, “F. Magrassi, A. Lanzara” Department of Clinical and Experimental Medicine and Surgery, Second University of Naples School of Medicine, c/o II Policlinico, Edificio 17, Via Pansini, 5, 80131 Naples, Italy;(2) Division of Medical Oncology, “F. Magrassi, A. Lanzara” Department of Clinical and Experimental Medicine and Surgery, Second University of Naples School of Medicine, Naples, Italy;(3) Division of Pathology, “F. Magrassi, A. Lanzara” Department of Clinical and Experimental Medicine and Surgery, Second University of Naples School of Medicine, Naples, Italy |
| Abstract: | BackgroundThe number of harvested (LNs) and metastatic nodes (LNs+) represents the most significant factor to define postoperative treatment and prognosis in colon cancer. However, its assessment may be inadequate causing an incorrect cancer staging. The lymph node ratio (LNR: the ratio between metastatic and resected nodes) has shown prognostic significance in many tumors; however, its role in colon cancer is not clearly elucidated. This study investigated LNR as a prognostic factor in node-positive colon cancers. |
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