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Infection during Infancy and Long Incubation Period of Leprosy Suggested in a Case of a Chimpanzee Used for Medical Research |
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| Authors: | Koichi Suzuki Toshifumi Udono Michiko Fujisawa Kazunari Tanigawa Gen'ichi Idani Norihisa Ishii |
| Affiliation: | Leprosy Research Center, National Institute of Infectious Diseases, Tokyo, Japan,1. Chimpanzee Sanctuary Uto, Sanwa Kagaku Kenkyusho, Kumamoto, Japan,2. Department of Welfare and Longevity Research, Wildlife Research Center, Kyoto University, Kyoto, Japan3. |
| Abstract: | The length of the incubation period of leprosy following Mycobacterium leprae infection has never been conclusively determined, owing to the lack of a method to demonstrate the presence of an asymptomatic infection. We report a rare case of leprosy in a chimpanzee in which a 30-year incubation period was strongly suggested by single nucleotide polymorphism (SNP) analysis. |
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