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Content of prostaglandins and cyclic AMP in rat tissue
Authors:Academician V. P. Komissarenko  V. N. Slavnov  E. V. Épshtein  V. D. Malinkovich
Affiliation:(1) Academy of Sciences of the Ukrainian SSR, Ukraine
Abstract:The content of prostaglandins (PG) and cyclic adenosine-3prime,5prime-monophosphate (cyclic AMP) in rat tissues was studied by a radioisotope method. The maximal content of both PG and cyclic AMP was found in the same organs, those functioning most actively: the brain, endocrine glands, and small intestine, and the minimal content in adipose tissue. The investigations show close functional interdependence between PG synthesis and adenylate cyclase activity in the tissues of the body.Kiev Scientific-Research Institute of Endocrinology and Metabolism. Translated from Byulleten' Éksperimental'noi Biologii i Meditsiny, Vol. 83, No. 4, pp. 416–418, April, 1977.
Keywords:prostaglandins  cyclic AMP  radioimmunological determination in the tissues
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