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帕金森病患者的认知电位研究
引用本文:潘红,蒋雨平,李盛昌. 帕金森病患者的认知电位研究[J]. 中国临床神经科学, 2002, 10(2): 169-171,174
作者姓名:潘红  蒋雨平  李盛昌
作者单位:复旦大学附属华山医院神经内科,200040
摘    要:目的 :研究帕金森病 (PD)患者认知功能损害。方法 :选取PD患者进行临床痴呆评分与简易智能测定 ,按照其结果将PD患者分为认知障碍组与认知正常组 ,分别进行事件相关电位检测 ,进行比较。结果 :PD认知正常组较正常对照组N2 、P3潜伏期延长 ,PD认知障碍组较PD认知正常组P3潜伏期延长。PD患者P3潜伏期与MMSE呈负相关 (r=- 0 41 5)。结论 :PD患者P3潜伏期延长 ,P3、MMSE均可反映PD患者的认知状况

关 键 词:帕金森病  认知  事件相关电位
文章编号:1008-0678(2002)01-0169-04
修稿时间:2001-06-26

Study of Event-related Potential in Parkinson'' s Disease
PAN Hong,JIANG Yu Ping,LI Sheng Chang. Study of Event-related Potential in Parkinson'' s Disease[J]. Chinese Journal of Clinical Neurosciences, 2002, 10(2): 169-171,174
Authors:PAN Hong  JIANG Yu Ping  LI Sheng Chang
Affiliation:PAN Hong,JIANG Yu Ping,LI Sheng Chang Department of Neurology,Huashan Hospital,Fudan University,Shanghai 200040,China
Abstract:Aim:To explore whether patients with PD have some damage in cognitive ability. Methods:We use Clinical Dementia Rating Scale and Mini Mental Examination to devide the PD patients into two groups: one is PD patients with cognitive impairment, the other is PD patients with normal cognition. To detect the PD patients event related potential and make a compare with the controls. Results: There is a negative correlation between P 3 latency and MMSE score. Conclusion:P 3 can also reflect the cognitive situation in PD patients together with MMSE.
Keywords:Parkinson's disease(PD) cognition event related potential
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