Brucella endocarditis associated with glomerulonephritis and renal vasculitis

We report a patient with a peculiar association of brucella endocarditis, glomerulonephritis, and renal vasculitis, with immunopathological features different from those of endocarditis glomerulonephritis. Renal biopsy revealed moderate diffuse hypercellularity involving the mesangium as well as capillary loops, immunoflurescence revealed no staining for IgG, IgM, IgA, C3, and fibrinogen. The clinical and biochemical evidence of glomerulonephritis disappeared after antibiotic treatment combined with steroid therapy. No similar case has been previously reported in the literature. Received September 5, 1995; received in revised form January 26, 1996; accepted February 5, 1996