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糖尿病性眼肌麻痹患者糖代谢与血液流变学相关性分析
引用本文:姚向荣,张全华,吕云利,李德明,赵波,廖军,刘吉耀,贾存玮. 糖尿病性眼肌麻痹患者糖代谢与血液流变学相关性分析[J]. 现代医学, 2011, 39(6): 680-683. DOI: 10.3969/j.issn.1671-7562.2011.06.017
作者姓名:姚向荣  张全华  吕云利  李德明  赵波  廖军  刘吉耀  贾存玮
作者单位:1. 兰州军区兰州总医院安宁分院 神经内科,甘肃兰州,730070
2. 兰州军区兰州总医院安宁分院 检验科,甘肃兰州,730070
3. 兰州军区兰州总医院安宁分院 消化内分泌科,甘肃兰州,730070
摘    要:目的:探讨2型糖尿病(T2DM)性眼肌麻痹(OMP)患者血糖、糖化血红蛋白(HbA1c)与血液流变学改变之间的关系。方法:对健康对照(HC)组48例、单纯T2DM组48例和T2DM+OMP组48例共144例研究对象进行隔夜空腹12 h血HbA1c、空腹血糖(FBG)、餐后2 h血糖(2 h-PG)及血液流变学检测,并进行相关性分析。结果:T2DM+OMP组除红细胞变形指数显著低于T2DM及HC组(P<0.01)外,HbA1c、FBG、2 h-PG及其他血液流变学指标均显著高于T2DM及HC组(均P<0.01);T2DM+OMP组红细胞变形指数与FBG、HbA1c呈负相关(r=-0.56、r=-0.81,P<0.01),全血黏度(低、中、高切)、血浆黏度、纤维蛋白原与血糖、HbA1c呈正相关(r介于0.35~0.88之间,P<0.05)。结论:高血糖、高黏血症是T2DM并发周围神经病变的危险因素,控制血糖、改善微循环对预防和治疗DM并发周围神经病变有指导意义。

关 键 词:糖尿病  眼肌麻痹  血糖  糖化血红蛋白  血液流变学

Correlation analysis of haemorheology and blood glucose metabolism in patients with diabetic ocular muscles palsy
YAO Xiang-rong,ZHANG Quan-hua,LU Yun-li,LI De-ming,ZHAO Bo,LIAO Jun,LIU Ji-yao,JIA Cun-wei. Correlation analysis of haemorheology and blood glucose metabolism in patients with diabetic ocular muscles palsy[J]. Modern Medical JOurnal, 2011, 39(6): 680-683. DOI: 10.3969/j.issn.1671-7562.2011.06.017
Authors:YAO Xiang-rong  ZHANG Quan-hua  LU Yun-li  LI De-ming  ZHAO Bo  LIAO Jun  LIU Ji-yao  JIA Cun-wei
Affiliation:YAO Xiang-rong1,ZHANG Quan-hua2,LU Yun-li1,LI De-ming3,ZHAO Bo1,LIAO Jun1,LIU Ji-yao1,JIA Cun-wei1 (1.Department of Neurology,2.Department of Clinical Laboratory,3.Department of Digestive and Endocrinology,Anning Branch of Lanzhou General Hospital of Lanzhou Military Command of PLA,Lanzhou 730070,China)
Abstract:Objective: To analyze the correlation between the change of the blood glucose,glycosylated hemoglobin(HbA1c) and haemorheological indices of patients with type 2 diabetic ocular muscles palsy. Methods: A total of 144 venous blood samples were collected from 48 glucose of patients with diabetic ocular muscles palsy(T2DM+OMP),48 glucose of patients without complication(T2DM) and 48 healthy controls(HC).The HbA1c,fasting blood glucose(FBG),postprandial blood glucose(2h-PG),haemorheological indices were measure...
Keywords:diabetes mellitus  ocular muscles palsy  glycosylated hemoglobin 1c  blood glucose  haemorheology  
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