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Glomerular mesangial fibrillary deposits in a patient with diabetes mellitus |
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| Authors: | Ipek Isık Gonul James Gough Kim Jim Hallgrimur Benediktsson |
| Institution: | (1) Staff pathologist, Department of Pathology, Gazi University Medical School, Ankara, Turkey;(2) Department of Pathology and Laboratory Medicine, University of Calgary, Calgary, Canada;(3) Department of Nephrology, University of Calgary, Calgary, Canada;(4) Department of Pathology and Laboratory Medicine, University of Calgary, Calgary, Canada;(5) 3443 Esplanade Ave, Apt 644, New Orleans, LA 70119, USA |
| Abstract: | Various systemic or primary glomerular diseases can result in deposition of fibrillary material in the glomerular tuft and may cause an important diagnostic challenge for the pathologists. Biopsy findings of a patient with type 2 diabetes is presented here in which striking fibrillary structures were identified in the mesangium by ultrastructural examination. The distinction between diabetic fibrillosis and fibrillary glomerulonephritis accompanying diabetic nephropathy is discussed in the setting of a literature review. |
| Keywords: | Diabetes Differential diagnosis Fibrillary glomerulonephritis Nephropathy |
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